Copper is taken up efficiently from albumin and 2-macroglobulin by cultured human cells by more than one mechanism
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چکیده
Mizue Moriya, Yi-Hsuan Ho, Anne Grana, Linh Nguyen, Arrissa Alvarez, Rita Jamil, M. Leigh Ackland, Agnes Michalczyk, Pia Hamer, Danny Ramos, Stephen Kim, Julian F. B. Mercer, and Maria C. Linder Department of Chemistry and Biochemistry and Institute for Molecular Biology and Nutrition, California State University, Fullerton, California; and Centre for Cellular and Molecular Biology, Deakin University, Burwood, Victoria, Australia
منابع مشابه
Copper is taken up efficiently from albumin and alpha2-macroglobulin by cultured human cells by more than one mechanism.
Ionic copper entering blood plasma binds tightly to albumin and the macroglobulin transcuprein. It then goes primarily to the liver and kidney except in lactation, where a large portion goes directly to the mammary gland. Little is known about how this copper is taken up from these plasma proteins. To examine this, the kinetics of uptake from purified human albumin and alpha(2)-macroglobulin, a...
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تاریخ انتشار 2008